THE
FIRST INDIAN SYMPOSIUM OF THE PROTEIN SOCIETY - Protein Structure &
Function
October
18-20, 2002
Venue:
PC Saxena Auditorium,
Indian
Institute of Technology Bombay, Mumbai, India
Program
Oct 18, 2002
8:30 – 10:15 Registration
10:15
– 10:45 Inaugural Function
Welcome address – Ashok
Misra, Director, IIT Bombay
Inaugural
Address – Manju Sharma,
Secretary,
Department of Biotechnology, New Delhi.
Remarks – Stephen H. White, Protein
Society
Remarks – Manoj Mishra, Head, Chemistry,
IIT Bombay
Remarks – Jayesh Bellare, Head, SBB, IIT
Bombay
Remarks – Dulal Panda (IITB), Secretary
Vote of Thanks – Anil K. Lala (IITB), Convener
10:45 – 11.30 G.N. Ramachandran lecture
Chairperson: A.S. Kolaskar
Harold A. Scheraga (Cornell)
ab initio
Prediction of Protein Structure by Global optimization of Potential Energy.
11:30 – 11:45 Tea
de novo protein
design
11:45 – 12:15 P. Balaram (IISc, Bangalore)
Conformationally
constrained residue in the design of protein mimics.
12:15
– 13:00 Robert M. Stroud
(UCSF)
The Glycerol Channel.
13:00 – 13:30 Lunch
13:30 – 14:00 M. Vijayan (IISc
Bangalore)
Structural
diversity and generation of ligand specificity in lectins.
14:00 – 14:30 Shekhar C. Mande
(CDFD Hyderabad)
Interesting
structural aspects of Mycobacterial chaperonins.
14:30 – 15:00 Dinakar M. Salunke (NII, Delhi)
Flexible
antigen and genetically independent antibodies: structural
convergence in an antibody response.
15:00 – 15:30 R.V. Hosur (TIFR, Mumbai)
Plasticity,
dynamics and folding of HIV-1 protease.
15:30 – 16:00 David J. Craik (Queensland, Australia)
Circular
Proteins in Nature.
16:00 – 16:30 Jim Samuelssom (BioBridge, Sweden)
Novel
Algorithms and Software for Automatic Protein Identification.
Protein
folding
Chairpersons:
M. Vijayan and Ch. Mohan Rao
16:50 – 17:20 Heinrich
Roder (FCCC, Philadelphia)
Structural
properties and kinetic role of early intermediates in protein folding.
17:20 – 17:50 Jayant
Udgaonkar (NCBS, Bangalore)
Structural
characterization of the folding of Barstar.
17:50 – 18:20 A.
Surolia (IISc, Bangalore)
Legume
lectins as paradigms for equilibrium folding studies of oligomeric proteins.
18:20 – 18:50 R.
Varadarajan (IISc, Bangalore)
Approaches to the design of temperature sensitive
mutants of a globular protein from amino acid sequence.
18:50 – 19:20 B.
Bhattacharyya (Bose Institute, Kolkata)
Chaperone
like activity of Tubulin.
______________________________________________
Oct 19, 2002
8:30 – 9:00 Girish Sahani (IMTECH, Chandigarh)
Deciphering
the molecular mechanism of the extraordinarily stringent substrate specificity
of the streptokinase-plasminogen activator complex: implications in the de
novo design of tailor-made proteases.
9:00 – 9:30 John E. Maggio (U Cincinnati college of
Medicine)
Folding
and misfolding in neurodegenerative disease: A-b
amyloid, and Alzheimer's.
9:30 – 10:00 Ehud Gazit (Tel-Aviv Univ, Israel)
The mechanism of Amyloid Fibrils Self-Assembly:
Implications for the Design of Fibrillization Inhibitors.
10:00 – 10:30 Eva -M. Mandelkow (Hamburg, Germany)
Role of tau protein in neurite outgrowth, axonal
traffic, and Alzheimer neurodegeneration.
10:30 – 10:50 Tea
10:50 – 11:20 Ch. Mohan Rao (CCMB, Hyderabad)
a crystallin: a small heat shock protein with chaperone
activity.
11:20 – 11:50 G. M. Anantharamiah (U Birmingham,
Alabama)
Peptide
mimics of antiatherogenic apoliporpotein A-1 and E.
11:50 – 12:20 R.M. Kini (NUS, Singapore)
Development
of a novel class of anticoagulant peptides based on the structure of a snake
venom prothrombin activator.
12:20 – 12:40 Rajesh S. Gokhale (NII, New Delhi)
Crosstalk
between fatty acid synthases and polyketide synthases in Mycobacterium tuberculosis.
12:40 – 13:00 Partha Saha (SINP, Kolkata)
Studies on two proteins from Leishmania donovani
to search for unique mechanism of cell cycle regulation in the parasite.
13:00
– 15:15 Lunch/Poster session
–1
15:15 – 16:00 J. P. Rosenbusch (U Basel, Switzerland)
Structure determination of membrane proteins to
atomic resolution: Problems and promise.
16:00 – 16:30 Ben Luisi (Cambridge, UK)
Structural
studies of TolA and TolB membrane proteins, and implications for transport
mechanisms.
16:30 – 17:00 William A. Cramer (Purdue)
Colicin-Receptor
Interactions.
17:00 – 17:30 Anil K. Lala
Organization
of Diphtheria toxin in membranes.
17:30 – 17:50 Tea
17:50 – 18:20 Jean-Marie Ruysschaert (Bruxelles,
Belgium)
Detection
of conformational changes in multidrug transporters.
18:20 – 18:50 S. Grissmer (Ulm,
Germany)
Toxins
and drugs modulating potassium channels
18:50 – 19:20 M. K. Mathew (NCBS)
Assembling
the Pieces of the Potassium Channel Jigsaw Puzzle: Chimeric Channels
Constrain Models
19:20 – 19:50 Michael P. Blanton (Texas Tech,
Lubbock)
The
Nicotinic Acetylcholine Receptor: Is the Membrane-spanning Domain Comprised of
a bundle of a-helices
or a mixture of a-helices and b-strands?
20:00 Dinner
______________________________________________
8:30 – 9:00 Stephen H. White (UC, Irvine)
How
membranes shape protein structure
9:00 – 9:30 Ashish Arora ( CDRI, Lucknow)
NMR
solution structure and dynamics of the Outer Membrane Protein A transmembrane
domain in detergent micelles
9:30 – 10:00 R. Nagraj (CCMB, Hyderabad)
Membrane-active
antimicrobial peptides: How important is structure in determining activity?
10:00 – 10:30 Satyajit Mayor (NCBS, Bangalore)
The
nano-scale structure of GPI-anchored protein containing rafts in living cell
10:30 – 11:00 Musti J. Swamy (University of Hyderabad, Hyderabad)
Interaction
of Bovine Seminal Plasma Protein, PDC-109 within Lipid Membranes
11:00
– 11:20 Tea
Cytoskeleton organization dynamics and diseased state
11:20 – 11:50 Les Wilson (UC, Santa Barbara)
Microtubule
dynamics and the mechanisms of action of microtubule-targeted antimitotic
anticancer drugs.
11:50 – 12:20 E.
Mandelkow (Hamburg, Germany)
Structure
of kinesin and interactions with microtubules
12:20 – 12:50 Amitabha Chattopadhyay (CCMB, Hyderabad)
Protein
Conformation and Dynamics using the Wavelength-Selective Fluorescence
Approach
12:50 – 15:00 Lunch/Poster session - 2
15:00 – 15:30 Daniel L. Purich (U Florida)
Actoclampin:
The Newly Recognized ATP-Dependent Motor Responsible for
Cell Crawling
15:30 – 16:00 Mark M. Rasenick (U Illinois)
Interaction
between G proteins and the cytoskeleton: Implications for depression and the
action of anti-depressant drugs
16:00 – 16:30 Dulal Panda (IIT, Bombay)
Antiproliferative
Mechanism of Action of Natural Flavonoids: Perturbation of Microtubule
Polymerization Dynamics Through Tubulin Binding
16:30 – 16:35 Concluding ceremony
16:35 Tea
19:00 Dinner