Year
Authors/Title/Journal
Nawale, G.; Gore, R. K.; Hobartner, C.; Pradeepkumar, P.I. Incorporation of 4'-C-aminomethyl-2'-O-methylthymidine into DNA by thermophilic DNA polymerases. ChemComm 2012, 48, 9619-9621
2012
Gore, K. R.; Nawale, G.; Harikrishna, S.; Chittoor, V; Pandey, S.; Hobartner, C; Patankar, S; Pradeepkumar, P.I. Synthesis, Gene Silencing and Molecular Modeling Studies of 4’-C-Aminomethyl, 2’-O-Methyl Modified Small Interfering RNAs. J. Org. Chem, 77, 3233-3245
2012
2012
Hobartner, C; Pradeepkumar, P. I. DNA Catalysts for Practical Application in Bioorganic Chemistry in New Strategies in Chemical Synthesis and Catalysis (Pigantaro, B. Ed.) , Wiley-VCH. Chapter 6, pp 129-150 Weblink: http://as.wiley.com/WileyCDA/WileyTitle/productCd-3527330909,descCd-tableOfContents.html
2012
Pradeepkumar, P. I.; Hobartner, C. RNA Cleaving DNA Enzymes and their Potential Therapeutic Applications as Antibacterial and Antiviral Agents in From Nucleic Acids Sequences to Molecular Medicine, (Erdmann, V. A, Barciszewski, J. Eds.), Springer Book Series in RNA Technologies, Springer DE. Chapter 15, pp 371-410 Weblink: http://www.springer.com/biomed/molecular/book/978-3-642-27425-1
2011
Wong, O. Y.; Pradeepkumar. P. I.; Silverman. S. K. DNA-Catalyzed Covalent Modification of Amino Acid Side Chains in Tethered and Free Peptide Substrates. Biochemistry, 50, 4741-4749
2010
Shukla, S.; Sumaria, C.; Pradeepkumar, P.I. Exploring Chemical Modifications for siRNA Therapeutics: A Structural and Functional Outlook, Chem Med Chem, 3, 328-349.
2008
Kost, D. M.; Gerdt, J. P.; Pradeepkumar, P. I.; Silverman, S. K. Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2',3'-cyclic phosphate RNA substrates, Org. Biomol. Chem., 6,4391-4398
2008
Pradeepkumar, P. I.; Hobartner, C.; Baum, A.; Silverman, S. K. DNA-catalyzed formation of nucleopeptide linkages, Angew. Chem. Int. Ed., 47, 1753-1757
2007
Hobartner, C.; Pradeepkumar, P. I.; Silverman, S. K. Site-selective depurination by a periodate-dependent deoxyribozyme, Chem. Commun., 14, 2255-2257
2005
Isaksson, J.; Plashkevych, O.; Pradeepkumar, P. I.; Chatterjee, S.; Barman, J.; Pathmasri, W.; Shrivastava, P.; Petit, C.; Chattopadhyaya, J. Oxetane locked thymidine in the Dickerson-Drew dodecamer causes local base pairing distortions - an NMR structure and hydration study, J. Biomol. Struct. Dyn., 23, 299-330
2004
Pradeepkumar, P. I.; Cheruku, P.; Plashkevych, O.; Acharya, P.; Gohil, S.; Chattopadhyaya, J. Synthesis,physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogs, J. Am. Chem. Soc, 126, 11484-11499
2004
Opalinska, J. B.; Kalota, A.; Rodriquez, L.; Henningson, C.; Gifford, L. K.; Lu,P.; Jen, K-Y.; Paradeepkumar, P. I.; Barman, J.; Kim, T. K.; Swider, C.;Chattopadhyaya, J.; Gewirtz, A.M. Rationally targeted, conformationally constrained, oxetane modified oligonucleotides are highly efficient gene silencing molecules, Nucleic Acids Res., 32, 5791-5799
2003
Pradeepkumar, P. I.; Amirkhanov, N. V.; Chattopadhyaya, J. Antisense oligonucleotides with oxetane-constrained cytidine enhance heteroduplex stability, elicit satisfactory RNase H response as well as show improved resistance to both exo and endonucleases, Org. Biomol. Chem., 1, 81-92
2003
Acharya, P.: Isaksson, J.; Pradeepkumar, P. I.; Chattopadhyaya, J. Three distinct sets of evidences show the importance of stereoelectronics as one of the major forces responsible for the self-assembly of DNA and RNA, Collect. Czech. Chem. Commun., 5, 99-120. (review)
2003
Amirkhanov, N.V.; Pradeepkumar, P. I.; Chattopadhyaya, J. Kinetic analysis of the RNA cleavage of the conformationally-constrained oxetane-modified antisense-RNA hybrid duplex by RNase H , J. Chem. Soc., Perkin Trans. 2, 976-984
2003
Boon, E.M.; Barton, J.K.; Pradeepkumar, P. I.; Isaksson, J.; Petit, C.; Chattopadhyaya, J. An electrochemical probe of DNA stacking in an antisense oligonucleotide containing C3'-endo locked sugar, Angew. Chem. Int. Ed, 41, 3402-3405
2001
Ossipov, D.; Pradeepkumar, P. I.; Holmer, M.; Chattopadhyaya, J. Synthesis of [Ru(phen)2DPPZ]2+-tethered oligo-DNA and studies on the metallointercalation mode into the DNA duplex, J. Am. Chem. Soc., 123, 3551-3562
2001
Zamaratski, E.; Ossipov, D.; Pradeepkumar, P. I.; Amirkhanov, N. V.;Chattopadhyaya, J. The 3'-modified antisense oligos promote faster hydrolysis of the target RNA by RNase H than the natural counterpart, Tetrahedron, 57, 593-606
2001
Pradeepkumar, P. I.; Zamaratski, E.; Foldesi, A.; Chattopadhyaya, J. Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H, J. Chem. Soc., Perkin Trans. 2, 402-408
2001
Pradeepkumar, P. I.; Chattopadhyaya J. Oxetane-modified antisense oligonucleotides promote RNase H cleavage of the complementary RNA strand in the hybrid duplex as efficiently as the native, and offer improved endonuclease resistance, J. Chem. Soc., Perkin Trans. 2, 2074-2083
2001
Zamaratski, E.; Pradeepkumar, P. I.; Chattopadhyaya, J. A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H, J. Biochem. Biophys. Methods, 48, 189-208. (review)
2000
Pradeepkumar, P. I.; Zamaratski, E.; Foldesi, A.; Chattopadhyaya, J. Transmission of the conformational information in the antisense/RNA hybrid duplex influences the pattern of the RNase H cleavage reaction, Tetrahedon Lett.,41, 8601-8607