ISCHA stands as one of the premier events in the realm of C-H activation. Since our inaugural symposium in Beijing, China, in 2012, we have traversed the globe to host gatherings in Rennes, France (2014); Montreal, Canada (2016); Yokohama, Japan (2018); and Göttingen, Germany (2022). Each symposium has left an indelible mark, propelling the discourse and advancements within the field. The ISCHA promises to be an exceptional gathering, bringing together leading researchers, scholars, and professionals from both industry and academia across the globe. This symposium aims to intensify scientific interaction, foster collaborations, and advance knowledge in the field of C-H activation. It is a pivotal platform for exchanging ideas, sharing insights, and exploring cutting-edge research in this domain.