Dr. Suvarn Kulkarni

    Associate Professor

    Department of Chemistry

    Indian Institute of Technology Bombay

    Powai, Mumbai 400076

    

    Ph:   022-2576 7166     

    Fax: 022 -2576 7152

    Email: suvarn[at]chem.iitb.ac.in

    Group Webpage

Academic Background

Ph. D. in Chemistry, 2001, University of Pune.


Professional Experience

Academia Sinica Post-doctoral Fellow - Academia Sinica, Taiwan (June 2001- Sept 2005)

Assistant Specialist - University of California Davis (Oct 2005 - July 2008)

Assistant Professor - Indian Association for the Cultivation of Science (Nov 2008 - Jan 2009)

Assistant Professor - Indian Institute of Technology Bombay (Feb 2009 - June 2012)

Associate Professor - Indian Institute of Technology Bombay (June 2012 - )

 

Research Interests

 

  • One-pot methods for glycomics.
  • Synthesis of cell-surface carbohydrates - oligosaccharides, glycolipids and glycoconjugates.
  • Study of carbohydrate recognition in infectious diseases and Cancer.

Representative Publications:

       
  • "Expeditious Synthesis of Mycobacterium tuberculosis Sulfolipids SL‑1 and Ac2SGL Analogues"- Sarpe, V. A.; Kulkarni, S. S., Org. Lett. 2014, 16(21), 5732-5735.   DOI :

  • "First Synthesis of Bacillus cereus Ch HF-PS Cell Wall Trisaccharide Repeating Unit" - Podilapu, A. R. ; Kulkarni, S. S.; Org. Lett.,  2014, 4336-4339.  DOI :

  • "Recent Advances in Synthesis of Bacterial Rare Sugar Building Blocks and Their Applications"- Emmadi, M.; Kulkarni, S. S., Nat. Prod. Rep., 2014,   DOI .

  • "Chemical Synthesis of Asparagine Linked Archaeal N-Glycan from Methanothermus Fervidus" - Sanapala, S. R.; Kulkarni, S. S., Chem. Eur. J. 2014,   20, 3578-3583   DOI

  • "Synthesis of Orthogonally Protected Bacterial, Rare Sugar and D-Glycosamine Building Blocks" - Emmadi, M.; Kulkarni, S. S. Nature Protocols 2013. 8, 1870 - 1889.

  • "Regioselective One Pot Protection of Glucose" Wang, C.-C.; Kulkarni, S. S.; Lee J.-C.; Luo, S.-Y.; Hung S.-C. Nature Protocols 2008, 3, 97-113

  • "Regioselective and One Pot Protection of Carbohydrates" Wang, C.-C.; Lee J.-C.; Luo, S.-Y.; Kulkarni, S. S.; Huang, Y.-W.; Lee, C.-C.; Chang, K.-L.; Hung S.-C. Nature 2007, 446, 896-899

  • "Cu(OTf)2-catalyzed Regioselective Reductive Ring Opening of Benzylidene Acetals" Shie, C.-R.; Tzeng, Z.-H.; Kulkarni, S. S.; Uang, B.-J.; Hsu, C.-Y.; Hung, S.-C. Angew. Chem. Int. Ed. 2005, 44, 1665-1668

  • "Synthesis of Heparin Oligosaccharides", Lee, J.-C.; Lu, X.-A.; Kulkarni, S. S.; Wen, Y.-S.; Hung, S.-C. J. Am. Chem. Soc. 2004, 126, 476-477

  • Click here to see the complete list of Publications.

Patents

 

  • One pot synthesis of unprotected alpha/beta-O-glycolipids' Gervay-Hague J.; Du, W.; Kulkarni, S. S.; Schombs, M. PCT Int. Appl.(2008), WO 2008124729 A1 20081016

  • Method for preparing hexose derivatives Hung, S.-C.; Wang, C.-C.; Lee, J.-C.; Luo, S.-Y.; Kulkarni, S. S.; Huang, Y. W.; Lee, C. C.; Chang, K. L., PCT Int. Appl. Publication No. US 7985856 B2 published on 26-Jul-2011 Application No. US 11/874697 filed on 18-Oct-2007.

Book Chapters

 

  • "Synthesis of Hemagglutinin-Binding Trisaccharides" Wang, C.-C.; Kulkarni , S. S.; Zulueta, M. M. L.; Hung, S.-C. In 'The Molecular Immunology of Complex Carbohydrates-3, Advances in Experimental Medicine and Biology 705, Springer Science+Business Media, LLC, 2011, Chapter 37, pp 691-726.

  • Glycosyl chlorides, bromides and iodides, Kulkarni, S.S. and Gervay-Hague, J. Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance, Demchenko, A. V. Eds., Wiley-VCH, 2008, pp59-93

  • Synthesis of glycolipid antigens, Kulkarni, S.S, and Gervay-Hague, J. In Chemical Glycobiology, Eds. Chen, X.; Halcomb, R.; Wang, P. G., ACS Symposium series 2008, 990, pp153-166