CH 528 : Natural Products

Syllabus

  • Terpenoids : Classification, structure,  chemistry and biogenesis of some important mono; sesqui, di, and triterpenes.         
  • Steroids : Sterols and bile acids, estrogens, androgens, gestogens and adrenocortical hormones. Hormone production. Cardiac glycosides. Steroidal triterpenes; biogenesis of steroids and correlation with terpenoids.
  • Alkaloids : Characteristic reactions, general methods of degradation, structure and chemistry of some well-known alkaloids.
  • Natural Pigments: Flavones, flavanones, isoflavones, xanthones, quinones, pterins, chlorophyll and haemin.
  • Carbohydrates: Stereochemistry, reaction and conformation of monosaccharides, deoxy and aminosugars, hexonic acid and vitamin C, disaccharides, polysaccharides, inositol; gan- gliosides and other glycosides. Chemistry of vitamins A,B,C and E.

Text References

  1. I. L. Finar, Organic Chemistry, Vol .2, 5th edition, ELBS, 1975.
  2. K. Nakanishi, T. Goto, S.Ito, S. Najori and S. Nozoe, Natural products Chemistry, Vol. 1 and 2, Academic Press, 1974.
  3. A. A. Newman, Chemistry of Terpenes and Terpenoids, Academic Press, 1972.
  4. W. Pelletier, Chemistry of the Alkaloids, Van Nostrand Reinhold, 1970.
  5. W.Shoppee, Chemistry of the Steroids, 2nd edition, Butter worths, 1964.
  6. D. Guthrie and J. Honeyman, An Introduction to the Chemistry of Carbohydratres, 3rd edition, Clarendon Press, 1968.
  7. A. Geissman, Chemistry of Flavonoid Compounds, Pergamomn Press, 1962.