Synthetic strategies and tactics, synthetic equivalents, normal and umpolung reactivity, methods of umpolung generation. Selective introduction and manipulation of functional groups, protecting groups, protecting group free approaches, latent functionality, retrosynthetic analysis. Formation of C-C and C-X (X = O, N, S etc) bonds via enolates, enamines, radicals, carbenoids, metal mediated coupling reactions, C-H activation/functionalization. Formation of C=C bonds via various olefination methods and metal mediated coupling reactions. Formation of carbon-carbon triple bonds. Thermal and photochemical reactions, cyclizations, cycloadditions and rearrangements, ene reaction. Selective oxidation and reduction methods. Multi-component and tandem reactions. Principles of regio- and stereocontrol and their applications in synthesis. Asymmetric synthesis via chiron, auxiliary and catalytic methods. Total synthesis of selected natural products and designed molecules.

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