Reconstitution and simulation of cellular motility in
micro-compartmentalized colloidal objects have important implications for
microcapsule-based remote sensing, environmentally induced signalling
between artificial cell-like entities, and programming spatial migration
to enable community level behaviour. In this talk, I will describe the
design and construction of catalase-containing organoclay/DNA
semipermeable microcapsules, which in the presence of hydrogen peroxide
exhibit enzyme-powered oxygen gas bubble-dependent buoyancy.
Co-encapsulation of catalase and glucose oxidase is exploited to establish
a spatiotemporal response to antagonistic bubble generation and depletion
to produce microcapsules capable of sustained oscillatory vertical
movement. The motility of the microcapsules is used for the flotation of
macroscopic objects, self-sorting of mixed microcapsule communities, and
delivery of a biocatalyst from an inert to chemically active environment.
These results highlight new opportunities for constructing programmable
micro-compartmentalized colloids with buoyancy-derived motility.