Seminar by Prof.Ola F. Wendt, Centre for Analysis and Synthesis, Department of Chemistry, Lund University, on "C–H activation and functionalisation using late transition metals"
15 Jan 2019
Seminar Room #350
Talk Title : "C–H activation and functionalisation using late transition metals"
Abstract
Direct one step conversion of unreactive carbon-hydrogen bonds into bonds with a desired functional group is a highly effective and rational way of producing bulk and fine chemicals, but it still remains a fundamental challenge in synthetic chemistry. Here we report on some different approaches towards understanding and application of C–H activation. Pincer complexes serve as model systems for understanding and developing C–H activation reactions and some examples involving multiple, reversible and low temperature C–H activations will be presented.
Problems remain in providing site selective functionalization of a single C–H bond within a complex organic molecule that contains numerous positions suitable for activation. We will show how this problem can be addressed. Furthermore, examples of recyclable catalysts will be discussed.