Sandip Kar

Professor

Room XXX, DESE-CESE Building
+91 22 2576 7193
Educational Background:

Ph.D., Indian Association for the Cultivation of Science, Kolkata
M. Sc.  University of Calcutta, Kolkata
B.Sc., Asutosh College, Kolkata
 

Professional Experience:

Post-doc, Virginia Polytechnic and State University, USA
Post-doc, German Cancer Research Center, Heidelberg, Germany.
Assistant Professor, IIT Bombay (2013 - 2018)
Associate Professor, IIT Bombay (2018)

Professor, IIT Bombay (August 2023)

Research Interest:

In the last few decades, biological research has become more and more interdisciplinary and diverse. The wealth of information gathered at the molecular level due to novel molecular biology techniques, encouraged biologists as well as many chemists and physicists to rethink about the fundamental processes that are regulated by different complex mechanisms in the cells of a human being. How different proteins dynamically regulate different events within the cell? How the cells sense extracellular signals? How cells react to any external perturbation? Are there certain network motifs that are repetitively involved in such regulatory mechanisms? How intrinsic and extrinsic noises influence the cell fate decisions? In our research, we would like to ask questions of these kinds by combining both experimental and theoretical approaches to understand the behavior of the different cellular signaling pathways and how they alter the cellular decision making processes under different situations. Obviously to explain such intriguing questions, one would require expertise from many disciplines to understand the regulatory mechanism behind these biological processes both qualitatively and quantitatively. We wish to tackle these kinds of problems theoretically by making suitable experimental collaborations to answer some of the relevant questions in biology in a systems biology framework. We think theoretical understanding of such complex biological events by keeping close relationship with the experimental findings, is the key to develop proper diagnostic measure for different types of life threatening diseases.
 

Publications:
Giri, Amitabha; Sengupta, Dola; Kar, Sandip.
ACS Chem. Neurosci. 2021, 12, 2360–2372

Samanta, Tagari; Kar, Sandip
J. Theo. Biol. 2021, 526, 110774.

Tikader, Baishakhi; Maji, Samir Kumar; Kar, Sandip
Chem. Sci. 2021, xx, xxxx.

Giri, Amitava; Jain, Shreyansh Pramod; Kar, Sandip.
ChemPhysChem 2020, 21, 1608 – 1616