Y. U. Sasidhar


308, Chemistry Bldg.
+91 22 2576 7179
Educational Background:

Ph.D., IIT Madras
M. Sc., IIT Madras

Professional Experience:

Visiting fellow, TIFR.

Assistant Professor, IIT Bombay (1989)

Associate Professor, IIT Bombay (1997)

Professor, IIT Bombay (2005)

Research Interest:

The major area of research in our group is Protein Folding and Dynamics. The mechanism by which an unfolded protein folds to its native and functional structure is called protein folding and deciphering the fundamental principles that underlie the process is the objective of our investigations. We study early folding events by considering peptide as well as protein models. We are also investigating the nature of the unfolded state under physiological conditions using peptide models. To achieve our objectives we use molecular dynamics technique.
The atomic level detailed structural information that we seek can not be obtained from experimental studies alone.We are also looking at the role played by protein dynamics in its function. Further we are interested in exploiting protein dynamics in the design of agonists and antagonists.

Apoorva Badaya, Yellamraju U. Sasidhar,
Journal of Molecular Graphics and Modelling, 111, 2022, 108098, https://doi.org/10.1016/j.jmgm.2021.108098

Gupta, Shubhangi; Sasidhar, Yellamraju U.
J. Mol. Graph. Model, 2019, 88, 71-80.

Gupta, Shubhangi; Sasidhar, Yellamraju U.
J. Phys. Chem. B, 2017, 121, 1268-1283