Seminar by Prof. Nagendra K. Sharma, School of Chemical Sciences, NISER - Bhubaneswar on "Synthesis and Evaluation of Non-benzenoid aromatic scaffold comprising Nucleic Acid and Peptides"

13 Oct 2023
Seminar Room # 350, second floor annex

Speaker: Prof. Nagendra K. Sharma
School of Chemical Sciences, National Institute of
Science Education and Research (NISER), Bhubaneswar,
Jatni Campus, 752050, (Odisha) India

Title: "Synthesis and Evaluation of Non-benzenoid aromatic
scaffold comprising Nucleic Acid and Peptides".

Day and Date: Friday, October 13, 2023

Time: 10.00 AM.

Venue: Seminar room, room no. 350,
Chemistry Department (second floor)
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Hosted by Prof. Pradeepkumar P.I.

Talk Title : "Synthesis and Evaluation of Non-benzenoid aromatic scaffold comprising Nucleic Acid and Peptides".
Abstract
Aromatic scaffold of nucleic acid (DNA/RNA) and peptides are derived from benzenoid aromatic moieties. However non-benzenoid aromatic scaffold such as Tropolone and Azulene are constituents of various natural products, possessing wide range of bioactivities such as antifungal, antibiotics, and anticancer. Thus, exploring these non-benzenoid aromatic scaffolds in the context of nucleic acids and peptides could open up new avenues in drug discovery and biotechnology. It may lead to the development of molecules with improved therapeutic properties or unique mechanisms of action, which could be valuable in the treatment of various diseases, including cancer, infections, and other medical conditions. However, extensive research and experimentation would be required to fully understand the potential and limitations of such modifications.